5G accelerates IoT proliferation in smart cities and industry 4.0. Device onboarding via Matter protocol ensures mutual auth. Edge gateways with AWS IoT Greengrass run ML inference for anomaly detection. PKI certificates from GlobalSign manage fleets. Runtime monitoring via Nozomi Networks spots protocol exploits. Zero Trust segmentation isolates critical assets. Compliance with NIST IR 8259A mandates risk assessments. This prevents Mirai-like botnets at scale.